BDBM2774 Alkenyldiarylmethane (ADAM) 16a::Alkenyldiarylmethanes (ADAM) 16a::Methyl 4,4-Dimethoxy-3,3-di(methoxycarbonyl)-5,5-dimethyl-6,6-diphenyl-5-hexenoate::methyl 2-methoxy-5-{6-methoxy-1-[4-methoxy-3-(methoxycarbonyl)-5-methylphenyl]-6-oxohex-1-en-1-yl}-3-methylbenzoate

SMILES [#6]-[#8]-[#6](=O)-[#6]-[#6]-[#6]\[#6]=[#6](/c1cc(-[#6])c(-[#8]-[#6])c(c1)-[#6](=O)-[#8]-[#6])-c1cc(-[#6])c(-[#8]-[#6])c(c1)-[#6](=O)-[#8]-[#6]

InChI Key InChIKey=LGDLIZZFXFWRNJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 2774   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Purdue University

LigandPNGBDBM2774(methyl 2-methoxy-5-{6-methoxy-1-[4-methoxy-3-(meth...)
Affinity DataIC50: 1.00E+3nMpH: 7.9Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Purdue University

LigandPNGBDBM2774(methyl 2-methoxy-5-{6-methoxy-1-[4-methoxy-3-(meth...)
Affinity DataIC50: 1.00E+3nMpH: 7.9Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2004
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM2774(methyl 2-methoxy-5-{6-methoxy-1-[4-methoxy-3-(meth...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed