BDBM27717 4-{4-[4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridin-1-yl]butyl}-1,2-dihydrophthalazin-1-one::phthalazinone analogue, 9b

SMILES Fc1ccc(cc1)C1=CCN(CCCCc2n[nH]c(=O)c3ccccc23)CC1

InChI Key InChIKey=QJXHLKDIFGACHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27717   

TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27717(4-{4-[4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridin...)
Affinity DataIC50: 49nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27717(4-{4-[4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridin...)
Affinity DataIC50: 84nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed