BDBM276060 2-[1-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]imidazol-4-yl]-4-(1H-triazol-4-yl)pyridine::US10071984, Example 22::US9896436, Example 22

SMILES FC(F)(F)c1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1Cl

InChI Key InChIKey=UETKJEROPXQZIY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 276060   

TargetLysine-specific demethylase 2B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM276060(2-[1-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]i...)
Affinity DataIC50: 100nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
Go to US Patent

TargetLysine-specific demethylase 2A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM276060(2-[1-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]i...)
Affinity DataIC50: 100nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
Go to US Patent

TargetIsoform 2 of Histone lysine demethylase PHF8 (2)(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM276060(2-[1-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]i...)
Affinity DataIC50: 550nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
Go to US Patent

TargetLysine-specific demethylase 2B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM276060(2-[1-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]i...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent

TargetLysine-specific demethylase 2A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM276060(2-[1-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]i...)
Affinity DataIC50: 100nMAssay Description:PHF8 Assay: The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction condit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent

TargetHistone lysine demethylase PHF8(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM276060(2-[1-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]i...)
Affinity DataIC50: 300nMAssay Description:PHF8 Assay: The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction condit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent