BDBM275768 CYCLIC CIDOFOVIR::Cyclic-hpmpc::US10071110, Compound Cyclic Cidofovir (cDCV)::US10071110, Compound cCDV

SMILES Nc1ccn(CC2COP(O)(=O)CO2)c(=O)n1

InChI Key InChIKey=YXQUGSXUDFTPLL-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 275768   

TargetFibroblast growth factor receptor 1(Human)
University of California

US Patent
LigandPNGBDBM275768(CYCLIC CIDOFOVIR | US10071110, Compound Cyclic Cid...)
Affinity DataEC50:  470nMAssay Description:Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 1(Human)
University of California

US Patent
LigandPNGBDBM275768(CYCLIC CIDOFOVIR | US10071110, Compound Cyclic Cid...)
Affinity DataEC50:  970nMAssay Description:The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 1(Human)
University of California

US Patent
LigandPNGBDBM275768(CYCLIC CIDOFOVIR | US10071110, Compound Cyclic Cid...)
Affinity DataEC50:  720nMAssay Description:The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
Go to US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
University of California

US Patent
LigandPNGBDBM275768(CYCLIC CIDOFOVIR | US10071110, Compound Cyclic Cid...)
Affinity DataEC50:  2.10E+3nMAssay Description:Subconfluent MRC-5 cells in 24-well culture dishes were inoculated by removing the medium and adding HSV-1 virus at a dilution that will result in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
Go to US Patent

TargetCapsid scaffolding protein(HHV-5)
University of California

US Patent
LigandPNGBDBM275768(CYCLIC CIDOFOVIR | US10071110, Compound Cyclic Cid...)
Affinity DataEC50:  470nMAssay Description:Antiviral assays for HCMV DNA were carried out by DNA hybridization as reported by Dankner, W. M., Scholl, D., Stanat, S. C., Martin, M., Souke, R. L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
Go to US Patent