BDBM275767 US10071110, Compound CDV::US10071110, Compound Cidofovir(CDV)

SMILES C1=CN(C(=O)N=C1N)C[C@H](CO)OCP(=O)(O)O

InChI Key InChIKey=VWFCHDSQECPREK-UHFFFAOYSA-N

Data  4 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 275767   

TargetFibroblast growth factor receptor 1(Human)
University of California

US Patent
LigandPNGBDBM275767(US10071110, Compound Cidofovir(CDV) | US10071110, ...)
Affinity DataEC50:  1.80E+3nMAssay Description:The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 1(Human)
University of California

US Patent
LigandPNGBDBM275767(US10071110, Compound Cidofovir(CDV) | US10071110, ...)
Affinity DataEC50:  2.10E+3nMAssay Description:The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
Go to US Patent

TargetCapsid scaffolding protein(HHV-5)
University of California

US Patent
LigandPNGBDBM275767(US10071110, Compound Cidofovir(CDV) | US10071110, ...)
Affinity DataEC50:  450nMAssay Description:Antiviral assays for HCMV DNA were carried out by DNA hybridization as reported by Dankner, W. M., Scholl, D., Stanat, S. C., Martin, M., Souke, R. L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 1(Human)
University of California

US Patent
LigandPNGBDBM275767(US10071110, Compound Cidofovir(CDV) | US10071110, ...)
Affinity DataEC50:  460nMAssay Description:Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
Go to US Patent