BDBM275392 1-[1-(2,6- difluorobenzyl)pyrrolidin-3- yl]-3-[1-(2-methylpyridin-4- yl)-1H-pyrazolo[3,4-c]pyridin- 5-yl]urea::US9884048, Example 271

SMILES Cc1cc(ccn1)-n1ncc2cc(NC(=O)NC3CCN(Cc4c(F)cccc4F)C3)ncc12

InChI Key InChIKey=JHKZVUGZPXSLMU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275392   

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM275392(1-[1-(2,6- difluorobenzyl)pyrrolidin-3- yl]-3-[1-(...)
Affinity DataIC50: 1nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
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Date in BDB:
12/12/2018
Entry Details
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