BDBM275248 (2S)-N-methyl-2-({[1-(2- methylpyridin-4-yl)-1H- pyrazolo[3,4-c]pyridin-5- yl]carbamoyl}amino)-2- phenylethanamide::US9884048, Example 142

SMILES CNC(=O)[C@@H](NC(=O)Nc1cc2cnn(-c3ccnc(C)c3)c2cn1)c1ccccc1

InChI Key InChIKey=QNLWZMSFBXUMRS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275248   

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM275248((2S)-N-methyl-2-({[1-(2- methylpyridin-4-yl)-1H- p...)
Affinity DataIC50: 1.09nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
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