BDBM275147 1-[(1R)-1-(3- chlorophenyl)ethyl]-3-[1-(2- methylpyridin-4-yl)-1H- pyrazolo[3,4-c]pyridin-5- yl]urea::US9884048, Example 43

SMILES C[C@@H](NC(=O)Nc1cc2cnn(-c3ccnc(C)c3)c2cn1)c1cccc(Cl)c1

InChI Key InChIKey=GGVKCLJMRZEGHM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275147   

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM275147(1-[(1R)-1-(3- chlorophenyl)ethyl]-3-[1-(2- methylp...)
Affinity DataIC50: 0.950nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
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