BDBM275136 N-{3-[({[1-(2- methylpyridin-4-yl)-1H- pyrazolo[3,4-c]pyridin-5- yl]carbamoyl}amino)methyl] phenyl}methanesulfonamide::US9884048, Example 32

SMILES Cc1cc(ccn1)-n1ncc2cc(NC(=O)NCc3cccc(NS(C)(=O)=O)c3)ncc12

InChI Key InChIKey=UAQXTYZVAOAEKL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275136   

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM275136(N-{3-[({[1-(2- methylpyridin-4-yl)-1H- pyrazolo[3,...)
Affinity DataIC50: 0.440nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
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