BDBM2746 3,3-Dichloro-4,4-dimethoxy-5,5-bis(methoxycarbonyl)-3,3-diphenylpropenoic Acid::3,3-bis[3-chloro-4-methoxy-5-(methoxycarbonyl)phenyl]prop-2-enoic acid::Alkenyldiarylmethane (ADAM) 14::Alkenyldiarylmethanes (ADAM) 14

SMILES [#6]-[#8]-[#6](=O)-c1cc(cc(Cl)c1-[#8]-[#6])-[#6](=[#6]\[#6](-[#8])=O)\c1cc(Cl)c(-[#8]-[#6])c(c1)-[#6](=O)-[#8]-[#6]

InChI Key InChIKey=WHBNRVNOPZRCQB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2746   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Purdue University

LigandPNGBDBM2746(3,3-Dichloro-4,4-dimethoxy-5,5-bis(methoxycarbonyl...)
Affinity DataIC50: 1.00E+5nMpH: 7.9Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2004
Entry Details Article
PubMed