BDBM27388 2-(2-chloropyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one::JMC502647 Compound 7::pyrrolopyridinone scaffold, 10

SMILES Clc1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1

InChI Key InChIKey=JTRXEPCDEVNYPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27388   

LigandPNGBDBM27388(JMC502647 Compound 7 | 2-(2-chloropyridin-4-yl)-1H...)
Affinity DataIC50: 147nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandPNGBDBM27388(JMC502647 Compound 7 | 2-(2-chloropyridin-4-yl)-1H...)
Affinity DataIC50: 608nMpH: 7.5 T: 2°CAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed