BDBM272990 (S)-2-((1-(2,5-difluoro- 4-(1H-1,2,4-triazol-5- yl)phenyl)-7,8,9,10- tetrahydro-6-oxa-2,10a- diazacycloocta[cd]inden- 4-yl)oxy)butanamide::US10065970, Example 295::US10435414, Example 295

SMILES CC[C@H](Oc1cc2OCCCCn3c(nc(c1)c23)-c1cc(F)c(cc1F)-c1ncn[nH]1)C(N)=O

InChI Key InChIKey=LUPKRCLEGWYINO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272990   

LigandPNGBDBM272990((S)-2-((1-(2,5-difluoro- 4-(1H-1,2,4-triazol-5- yl...)
Affinity DataKi:  0.0530nMAssay Description:PI3K Binding assays are intended for determining the biochemical potency of small molecule PI3K inhibitors. The PI3K lipid kinase reaction is perform...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
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LigandPNGBDBM272990((S)-2-((1-(2,5-difluoro- 4-(1H-1,2,4-triazol-5- yl...)
Affinity DataKi:  0.0530nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent