BDBM272942 (S)-1-(1-(2- aminobenzo[d]oxazol- 5-yl)-3-fluoro-7,8,9,10- tetrahydro-6-oxa-2,10a- diazacycloocta[cd]inden- 4-yl)pyrrolidine-2- carboxamide::US10065970, Example 247

SMILES Nc1nc2cc(ccc2o1)-c1nc2c(F)c(cc3OCCCCn1c23)N1CCC[C@H]1C(F)=O

InChI Key InChIKey=JAHOJPSUZUWFCI-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 272942   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Genentech

US Patent

LigandBDBM272942((S)-1-(1-(2- aminobenzo[d]oxazol- 5-yl)-3-fluoro-7...)Copy SMILESCopy InChI

Affinity DataKi:  0.0240nMAssay Description:PI3K Binding assays are intended for determining the biochemical potency of small molecule PI3K inhibitors. The PI3K lipid kinase reaction is perform...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/11/2018
Entry Details
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