BDBM272599 2-amino-N-(1-(4-chloro-1-methyl-7-phenyl-1H-indazol-6-yl)ethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide trifluoroacetate & 2-amino-N-(1-(4-chloro-2-methyl-7-phenyl-2H-indazol-6-yl)ethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide trifluoroacetate::US10065963, Example 15::US10065963, Example 16

SMILES CC(NC(=O)c1c(N)nn2cccnc12)c1cc(Cl)c2cnn(C)c2c1-c1ccccc1

InChI Key InChIKey=VWFONRUQJDLCKG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 272599   

LigandPNGBDBM272599(2-amino-N-(1-(4-chloro-1-methyl-7-phenyl-1H-indazo...)
Affinity DataIC50: 100nMpH: 6.7 T: 2°CAssay Description:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...More data for this Ligand-Target Pair
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Date in BDB:
12/11/2018
Entry Details
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LigandPNGBDBM272599(2-amino-N-(1-(4-chloro-1-methyl-7-phenyl-1H-indazo...)
Affinity DataIC50: 500nMpH: 6.7 T: 2°CAssay Description:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
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LigandPNGBDBM272599(2-amino-N-(1-(4-chloro-1-methyl-7-phenyl-1H-indazo...)
Affinity DataIC50: 1.00E+3nMAssay Description:To measure the Phosphorylated Ribosomal Protein S6 (RPS6) in cell lysates, THP-1 cells (Human Acute Monocytic Leukemia) are purchased from ATCC (Mana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
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LigandPNGBDBM272599(2-amino-N-(1-(4-chloro-1-methyl-7-phenyl-1H-indazo...)
Affinity DataIC50: 500nMpH: 6.7 T: 2°CAssay Description:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

LigandPNGBDBM272599(2-amino-N-(1-(4-chloro-1-methyl-7-phenyl-1H-indazo...)
Affinity DataIC50: 2.00E+3nMpH: 6.7 T: 2°CAssay Description:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent