BDBM272140 E1-(abs)-2-(1,5-Dimethyl-1H-pyrazol-4-yl)-5-(3- fluoro-2-methylphenyl)-N-hydroxy-5,6-dihydro-4H- cyclopenta[d]thiazole-5-carboxamide::US10065948, 76::US10065948, 77::US10457675, Example 77

SMILES Cc1c(cnn1C)-c1nc2CC(Cc2s1)(C(=O)NO)c1cccc(F)c1C

InChI Key InChIKey=UOWMFUOXSDIDNI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 272140   

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272140(US10065948, 77 | E1-(abs)-2-(1,5-Dimethyl-1H-pyraz...)
Affinity DataIC50: 68nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272140(US10065948, 77 | E1-(abs)-2-(1,5-Dimethyl-1H-pyraz...)
Affinity DataIC50: 200nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272140(US10065948, 77 | E1-(abs)-2-(1,5-Dimethyl-1H-pyraz...)
Affinity DataIC50: 68nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272140(US10065948, 77 | E1-(abs)-2-(1,5-Dimethyl-1H-pyraz...)
Affinity DataIC50: 200nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent