BDBM272123 (R)-1-Cyclopropyl-4-(3-fluoro-2-methylphenyl)-N- hydroxy-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-4- carboxamide::US10065948, 59::US10457675, Example 59

SMILES Cc1c(F)cccc1[C@@]1(CCc2c1cnn2C1CC1)C(=O)NO

InChI Key InChIKey=XCBZYRURMRLFTD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272123   

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272123((R)-1-Cyclopropyl-4-(3-fluoro-2-methylphenyl)-N- h...)
Affinity DataIC50: 100nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272123((R)-1-Cyclopropyl-4-(3-fluoro-2-methylphenyl)-N- h...)
Affinity DataIC50: 100nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent