BDBM272113 (R)-2-(2-Chlorophenyl)-5-(3-fluoro-2-methylphenyl)- N-hydroxy-6,7-dihydro-5H-cyclopenta[d]pyrimidine- 5-carboxamide::US10065948, 49::US10457675, Example 49

SMILES Cc1c(F)cccc1[C@@]1(CCc2nc(ncc12)-c1ccccc1Cl)C(=O)NO

InChI Key InChIKey=CBWMOTKRRHVTON-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272113   

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272113((R)-2-(2-Chlorophenyl)-5-(3-fluoro-2-methylphenyl)...)
Affinity DataIC50: 102nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
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TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272113((R)-2-(2-Chlorophenyl)-5-(3-fluoro-2-methylphenyl)...)
Affinity DataIC50: 102nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent