BDBM272093 (S)-5-(3-Fluoro-2-methylphenyl)-2-(3-fluoropyridin-2- yl)-N-hydroxy-2,4,5,6-tetrahydrocyclopenta[c]pyrazole- 5-carboxamide::US10065948, 29::US10457675, Example 29

SMILES Cc1c(F)cccc1[C@@]1(Cc2cn(nc2C1)-c1ncccc1F)C(=O)NO

InChI Key InChIKey=WKAMXVLNHDYKNP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272093   

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272093((S)-5-(3-Fluoro-2-methylphenyl)-2-(3-fluoropyridin...)
Affinity DataIC50: 104nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272093((S)-5-(3-Fluoro-2-methylphenyl)-2-(3-fluoropyridin...)
Affinity DataIC50: 104nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent