BDBM272092 (S)-2-(3-Chloropyridin-2-yl)-5-(3-fluoro-2- methylphenyl)-N-hydroxy-2,4,5,6- tetrahydrocyclopenta[c]pyrazole-5-carboxamide::US10065948, 28::US10457675, Example 28

SMILES Cc1c(F)cccc1[C@@]1(Cc2cn(nc2C1)-c1ncccc1Cl)C(=O)NO

InChI Key InChIKey=XBHIHMLNYYWNTI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272092   

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272092((S)-2-(3-Chloropyridin-2-yl)-5-(3-fluoro-2- methyl...)
Affinity DataIC50: 65nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272092((S)-2-(3-Chloropyridin-2-yl)-5-(3-fluoro-2- methyl...)
Affinity DataIC50: 65nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent