BDBM272090 (S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1-(3- methylpyridin-4-yl)-1,4,5,6- tetrahydrocyclopenta[c]pyrazole-5-carboxamide::US10065948, 26::US10457675, Example 26

SMILES Cc1cnccc1-n1ncc2C[C@@](Cc12)(C(=O)NO)c1cccc(F)c1C

InChI Key InChIKey=HPZDBSDQBRXMGE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272090   

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272090((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1-(3- me...)
Affinity DataIC50: 57nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272090((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1-(3- me...)
Affinity DataIC50: 57nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent