BDBM272073 (S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1-(p- tolyl)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-5- carboxamide::US10065948, 9::US10457675, Example 9

SMILES Cc1ccc(cc1)-n1ncc2C[C@@](Cc12)(C(=O)NO)c1cccc(F)c1C

InChI Key InChIKey=LRFKWFKOFXFFHK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272073   

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272073((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1-(p- to...)
Affinity DataIC50: 39nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272073((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1-(p- to...)
Affinity DataIC50: 39nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent