BDBM271665 US10065941, Compound R-009::US9732060, Compound R-009

SMILES COc1cc(Oc2ccc(cc2)\N=c2/[nH]c(=O)n([C@@H](C)[C@@H](C)C(O)=O)c(=O)n2Cc2ccc(Cl)cc2)ccn1

InChI Key InChIKey=VHCWZTCHUCJFFM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 271665   

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandPNGBDBM271665(US10065941, Compound R-009 | US9732060, Compound R...)
Affinity DataIC50: 7nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
Shionogi

US Patent
LigandPNGBDBM271665(US10065941, Compound R-009 | US9732060, Compound R...)
Affinity DataIC50: 4nMAssay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The C6BU-1 cells were seeded in a 96-well microtiter plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandPNGBDBM271665(US10065941, Compound R-009 | US9732060, Compound R...)
Affinity DataIC50: 7nMAssay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
Shionogi

US Patent
LigandPNGBDBM271665(US10065941, Compound R-009 | US9732060, Compound R...)
Affinity DataIC50: 4nMAssay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The C6BU-1 cells were seeded in a 96-well microtiter plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
Go to US Patent