BDBM271537 US10065941, Compound I-038::US9732060, Compound I-038

SMILES C[C@@H](Cn1c(=O)[nH]\c(=N/c2ccc(Oc3ccc(cn3)C(F)(F)F)cc2)n(Cc2ccc(C)cc2)c1=O)C(O)=O

InChI Key InChIKey=LPXZNUIGAZFYLF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 271537   

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandPNGBDBM271537(US10065941, Compound I-038 | US9732060, Compound I...)
Affinity DataIC50: 5nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandPNGBDBM271537(US10065941, Compound I-038 | US9732060, Compound I...)
Affinity DataIC50: 5nMAssay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
Go to US Patent