BDBM271477 2-(7-(2-chloro-3-fluorophenoxy)-4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxamido)acetic acid::US10065928, Example 24

SMILES Cn1c2cc(Oc3cccc(F)c3Cl)ccc2c(O)c(C(=O)NCC(O)=O)c1=O

InChI Key InChIKey=SDFAGJDIQJTWBW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 271477   

TargetHypoxia-inducible factor 1-alpha(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM271477(2-(7-(2-chloro-3-fluorophenoxy)-4-hydroxy-1-methyl...)
Affinity DataEC50:  9.53E+3nMAssay Description:The activities of compounds of the invention in inducing erythropoietin (EPO) production were assessed by using human live cancer cell strain Hep3B (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent