BDBM271352 US10064861, Compound 7

SMILES O=C1Nc2nc3ccccc3n2Cc2cncc(c2)-c2ccc(=O)n(Cc3cccc1c3)n2

InChI Key InChIKey=ORCFKMWGWDFXHB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 271352   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Patent

US Patent
LigandPNGBDBM271352(US10064861, Compound 7)
Affinity DataIC50: 100nMpH: 7.0Assay Description:IRAK4 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712) IRAK4 hydrolyses ATP, autophosphorylates and phosphorylates a Serine/Threonine ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent