BDBM27095 2-[(2S)-pyrrolidin-2-yl]-1H-1,3-benzodiazole-4-carboxamide::JMC52514 Compound 4b::cyclic amine-containing benzimidazole carboxamide, 6

SMILES NC(=O)c1cccc2nc([nH]c12)[C@@H]1CCCN1

InChI Key InChIKey=HTZYXVMVVCKCTD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27095   

TargetPoly [ADP-ribose] polymerase 1(Human)
Abbott Laboratories

LigandPNGBDBM27095(JMC52514 Compound 4b | 2-[(2S)-pyrrolidin-2-yl]-1H...)
Affinity DataKi:  30nM ΔG°:  -10.2kcal/molepH: 8.0 T: 2°CAssay Description:PARP assays utilizing SPA bead-based detection were carried out in 96-well plates. After reaction was terminated, the reaction mixtures were transfer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Abbott Laboratories

LigandPNGBDBM27095(JMC52514 Compound 4b | 2-[(2S)-pyrrolidin-2-yl]-1H...)
Affinity DataKi:  30nM ΔG°:  -10.2kcal/molepH: 8.0 T: 2°CAssay Description:PARP assays utilizing SPA bead-based detection were carried out in 96-well plates. After reaction was terminated, the reaction mixtures were transfer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2009
Entry Details Article
PubMed