BDBM270467 US10059668, Example 30::US10059668, Example 42

SMILES CCS(=O)(=O)NC(=O)c1ccc(CN2CCC(CC2)N[C@@H]2C[C@H]2c2ccccc2)cc1

InChI Key InChIKey=DYWQLKWJFXHDEC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 270467   

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandPNGBDBM270467(US10059668, Example 42 | US10059668, Example 30)
Affinity DataIC50: 127nMpH: 7.5 T: 2°CAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandPNGBDBM270467(US10059668, Example 42 | US10059668, Example 30)
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent