BDBM270299 US10059667, Example 20

SMILES COc1ccc(F)cc1CN1CCC(COc2cccc(c2)[C@@H](CC(O)=O)C2CC2)C1

InChI Key InChIKey=FUHRGXFWJSBYEG-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 270299   

TargetFree fatty acid receptor 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM270299(US10059667, Example 20)
Affinity DataEC50:  266nMpH: 7.4 T: 2°CAssay Description:FLIPR (Fluorimetric Imaging Plate Reader, Molecular Devices) assays were performed to measure agonist-induced calcium mobilization of the stable clon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM270299(US10059667, Example 20)
Affinity DataEC50:  1.00E+4nMT: 2°CAssay Description:The assay was performed in 96-well format. HEK cells stably expressing human GPR40 were plated to be 60-80% confluent within 72 h. After 72 h, the pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent