BDBM269481 (E)-3-(4-((2-(2- isopropylphenyl)-6- (propionyloxy)benzo[b] thiophen-3- yl)oxy)phenyl)acrylic acid::US10058534, 136

SMILES CCC(=O)Oc1ccc2c(Oc3ccc(\C=C\C(O)=O)cc3)c(sc2c1)-c1ccccc1C(C)C

InChI Key InChIKey=LZVSEZPUDQJZGO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 269481   

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandPNGBDBM269481((E)-3-(4-((2-(2- isopropylphenyl)-6- (propionyloxy...)
Affinity DataIC50: 5.10nMpH: 5.1 T: 2°CAssay Description:The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent