BDBM269441 (E)-3-(4-((6-hydroxy-2- (2-((2-methyl-2H- tetrazol-5- yl)methyl)phenyl)benzo [b]thiophen-3- yl)oxy)phenyl)acrylic acid::US10058534, 96

SMILES Cn1nnc(Cc2ccccc2-c2sc3cc(O)ccc3c2Oc2ccc(\C=C\C(O)=O)cc2)n1

InChI Key InChIKey=NZTOUEOBTSJJHI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 269441   

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandPNGBDBM269441((E)-3-(4-((6-hydroxy-2- (2-((2-methyl-2H- tetrazol...)
Affinity DataIC50: 212nMpH: 5.1 T: 2°CAssay Description:The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandPNGBDBM269441((E)-3-(4-((6-hydroxy-2- (2-((2-methyl-2H- tetrazol...)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent