BDBM26931 8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)-3-(2-oxopropyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::spiropiperidine analogue, 52

SMILES CC(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C2CCC(C)(C)c3ccccc23)C1=O

InChI Key InChIKey=SFJKZKRGYFETAG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26931   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

LigandPNGBDBM26931(8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  4.5nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

LigandPNGBDBM26931(8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  14nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Schering-Plough Research Institute

LigandPNGBDBM26931(8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  56nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Schering-Plough Research Institute

LigandPNGBDBM26931(8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  795nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2009
Entry Details Article
PubMed