BDBM268610 2,5-Dichloro-N-[4-(4-pyridin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)-phenyl]-benzenesulfonamide::US9718825, Example 5

SMILES Clc1ccc(Cl)c(c1)S(=O)(=O)Nc1ccc(cc1)-c1nc(-c2cccnc2)c2cn[nH]c2n1

InChI Key InChIKey=XSJPHHZGWQTVTB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 268610   

TargetSerine/threonine-protein kinase Sgk1(Human)
Sanofi

US Patent
LigandPNGBDBM268610(2,5-Dichloro-N-[4-(4-pyridin-3-yl-1H-pyrazolo[3,4-...)
Affinity DataIC50: 1.20nMpH: 7.4Assay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
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