BDBM268526 N-(6-cyclopropyl-7-((3,5-dichlorophenoxy)methyl)-[1,2,4]-triazolo[4,3-a]pyridin-3-yl)-1-methylcyclopropane-1-sulfonamide::US9550775, 105::US9550775, 50

SMILES CC1(CC1)S(=O)(=O)Nc1nnc2cc(COc3cc(Cl)cc(Cl)c3)c(cn12)C1CC1

InChI Key InChIKey=ODGYNZZVQHUUHU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 268526   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM268526(US9550775, 105 | N-(6-cyclopropyl-7-((3,5-dichloro...)
Affinity DataIC50: 4.87nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
Go to US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM268526(US9550775, 105 | N-(6-cyclopropyl-7-((3,5-dichloro...)
Affinity DataIC50: 5nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
Go to US Patent