BDBM268523 N-(7-((3-chloro-5-methylphenoxy)methyl)-6-cyclopropyl-[1,2,4]triazolo[4,3-a]pyridin-3-yl)methanesulfonamide::US9550775, 102::US9550775, 47

SMILES Cc1cc(Cl)cc(OCc2cc3nnc(NS(C)(=O)=O)n3cc2C2CC2)c1

InChI Key InChIKey=KITPJBHIQDAAAH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 268523   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM268523(N-(7-((3-chloro-5-methylphenoxy)methyl)-6-cyclopro...)
Affinity DataIC50: 7.29nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
Go to US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM268523(N-(7-((3-chloro-5-methylphenoxy)methyl)-6-cyclopro...)
Affinity DataIC50: 7nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
Go to US Patent