BDBM268520 N-(7-((3-chloro-5-(trifluoromethoxy)phenoxy)methyl)-6-cyclopropyl-[1,2,4]triazolo[4,3-a]pyridin-3-yl)azetidine-1-sulfonamide)::US9550775, 44::US9550775, 99

SMILES FC(F)(F)Oc1cc(Cl)cc(OCc2cc3nnc(NS(=O)(=O)N4CCC4)n3cc2C2CC2)c1

InChI Key InChIKey=YCCSXINQQOYFOF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 268520   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM268520(US9550775, 99 | N-(7-((3-chloro-5-(trifluoromethox...)
Affinity DataIC50: 7.33nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
Go to US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM268520(US9550775, 99 | N-(7-((3-chloro-5-(trifluoromethox...)
Affinity DataIC50: 7nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
Go to US Patent