BDBM268503 N-(6-cyclopropyl-7-(((1S,2S,5S)-6,6-dimethylbicyclo[3.1.1]heptan-2-yl)methoxy)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)methanesulfonamide::US9550775, 28::US9550775, 83

SMILES CC1(C)[C@@H]2C[C@H]1[C@@H](COc1cc3nnc(NS(C)(=O)=O)n3cc1C1CC1)CC2

InChI Key InChIKey=DULHSWPUJBKMQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 268503   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM268503(US9550775, 83 | N-(6-cyclopropyl-7-(((1S,2S,5S)-6,...)
Affinity DataIC50: 2.60nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
Go to US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM268503(US9550775, 83 | N-(6-cyclopropyl-7-(((1S,2S,5S)-6,...)
Affinity DataIC50: 3nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
Go to US Patent