BDBM268447 4-[3-(2-chloro-6-cyclopropyl- benzoyl)imidazo[1,5-a]pyridin-1- yl]-3-(hydroxymethyl)benzoic acid::US9550771, Example 46

SMILES OCc1cc(ccc1-c1nc(C(=O)c2c(Cl)cccc2C2CC2)n2ccccc12)C(O)=O

InChI Key InChIKey=ICEVEDHMYRVPDH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 268447   

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandPNGBDBM268447(4-[3-(2-chloro-6-cyclopropyl- benzoyl)imidazo[1,5-...)
Affinity DataEC50:  109nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
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