BDBM268432 4-[3-(2-chloro-6-prop-1-ynyl- benzoyl)imidazo[1,5-a]pyridin-1- yl]benzoic acid::US9550771, Example 31

SMILES CC#Cc1cccc(Cl)c1C(=O)c1nc(-c2ccc(cc2)C(O)=O)c2ccccn12

InChI Key InChIKey=CWOSGIROISSPTK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 268432   

TargetNuclear receptor ROR-gamma [262-507](Human)
Genentech

US Patent
LigandPNGBDBM268432(4-[3-(2-chloro-6-prop-1-ynyl- benzoyl)imidazo[1,5-...)
Affinity DataEC50:  202nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
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