BDBM267488 4-(8-amino-3-((trans)-4-hydroxycyclohexyl)imidazo[1,5-a]pyrazin-1-yl)-N-(6,7-dihydro-4H-pyrano[4,3-d]thiazol-2-yl)benzamide::US9718828, Example, 16
SMILES Cc1cc(ccc1-c1nc([C@H]2CC[C@H](O)CC2)n2ccnc(N)c12)C(=O)Nc1ccccn1
InChI Key InChIKey=HLXFENUNSACAHV-UHFFFAOYSA-N
Data 1 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 267488
Affinity DataEC50: 550nMpH: 7.2 T: 2°CAssay Description:Btk enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below. Btk enzyme (...More data for this Ligand-Target Pair