BDBM267470 US9718822, 45 Diastereomer 2

SMILES O[C@@H]1CNC(=O)c2cnn3ccc(nc23)N2CC(F)(F)CC2c2cc(F)ccc2OC1

InChI Key InChIKey=RQZIXOOARXBNHW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 267470   

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandPNGBDBM267470(US9718822, 45 Diastereomer 2)
Affinity DataIC50: 55nMpH: 7.5Assay Description:The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen Eu Kinase Binding Assay. In this assay, His-tagged recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
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