BDBM26735 N-{4-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]phenyl}-1-(thiophene-2-sulfonyl)piperidine-4-carboxamide::thiazole analogue, 17c

SMILES Clc1ccc(cc1)-c1csc(n1)-c1ccc(NC(=O)C2CCN(CC2)S(=O)(=O)c2cccs2)cc1

InChI Key InChIKey=KITAQLKJYXMOGL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26735   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Abbott Laboratories

LigandPNGBDBM26735(N-{4-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]phenyl}-...)
Affinity DataIC50: 44nMpH: 8.0 T: 2°CAssay Description:[3H]anandamide was incubated with membranes to produce radiolabeled ethanolamine and unlabeled arachidonic acid. Charcoal selectively binds anandamid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2009
Entry Details Article
PubMed