BDBM26732 Benzothiazole-based analogue, 1::N-[4-(4-methoxy-1,3-benzothiazol-2-yl)phenyl]-1-(thiophene-2-sulfonyl)piperidine-4-carboxamide::benzothiazole analogue, 16j

SMILES COc1cccc2sc(nc12)-c1ccc(NC(=O)C2CCN(CC2)S(=O)(=O)c2cccs2)cc1

InChI Key InChIKey=RNXVEWJEICSYKI-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 26732   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Abbott Laboratories

LigandPNGBDBM26732(Benzothiazole-based analogue, 1 | N-[4-(4-methoxy-...)
Affinity DataIC50: 1.70nMpH: 8.0 T: 2°CAssay Description:[3H]anandamide was incubated with membranes to produce radiolabeled ethanolamine and unlabeled arachidonic acid. Charcoal selectively binds anandamid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Astrazeneca Pharmaceuticals

LigandPNGBDBM26732(Benzothiazole-based analogue, 1 | N-[4-(4-methoxy-...)
Affinity DataIC50: 2nMpH: 8.0 T: 2°CAssay Description:the enzyme activity of recombinant human FAAH was measured according to published procedures with minor modifications by either a fluorescent assay u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Astrazeneca Pharmaceuticals

LigandPNGBDBM26732(Benzothiazole-based analogue, 1 | N-[4-(4-methoxy-...)
Affinity DataIC50: 2.10nMpH: 8.0 T: 2°CAssay Description:the enzyme activity of recombinant human FAAH was measured according to published procedures with minor modifications by either a fluorescent assay u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Astrazeneca Pharmaceuticals

LigandPNGBDBM26732(Benzothiazole-based analogue, 1 | N-[4-(4-methoxy-...)
Affinity DataIC50: 2nMpH: 8.0 T: 2°CAssay Description:the enzyme activity of recombinant human FAAH was measured according to published procedures with minor modifications by either a fluorescent assay u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Astrazeneca Pharmaceuticals

LigandPNGBDBM26732(Benzothiazole-based analogue, 1 | N-[4-(4-methoxy-...)
Affinity DataIC50: 2.30nMpH: 8.0 T: 2°CAssay Description:the enzyme activity of recombinant human FAAH was measured according to published procedures with minor modifications by either a fluorescent assay u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Astrazeneca Pharmaceuticals

LigandPNGBDBM26732(Benzothiazole-based analogue, 1 | N-[4-(4-methoxy-...)
Affinity DataIC50: 2.5nMpH: 8.0 T: 2°CAssay Description:the enzyme activity of recombinant human FAAH was measured according to published procedures with minor modifications by either a fluorescent assay u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Astrazeneca Pharmaceuticals

LigandPNGBDBM26732(Benzothiazole-based analogue, 1 | N-[4-(4-methoxy-...)
Affinity DataIC50: 5.10nMpH: 8.0 T: 2°CAssay Description:the enzyme activity of recombinant human FAAH was measured according to published procedures with minor modifications by either a fluorescent assay u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Astrazeneca Pharmaceuticals

LigandPNGBDBM26732(Benzothiazole-based analogue, 1 | N-[4-(4-methoxy-...)
Affinity DataIC50: 5.10nMpH: 8.0 T: 2°CAssay Description:the enzyme activity of recombinant human FAAH was measured according to published procedures with minor modifications by either a fluorescent assay u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Astrazeneca Pharmaceuticals

LigandPNGBDBM26732(Benzothiazole-based analogue, 1 | N-[4-(4-methoxy-...)
Affinity DataIC50: 3.80nMpH: 8.0 T: 2°CAssay Description:the enzyme activity of recombinant human FAAH was measured according to published procedures with minor modifications by either a fluorescent assay u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2013
Entry Details Article
PubMed