BDBM267190 N-{2-[2-(4,4-difluorocyclohexyl)-1,3-thiazol-5-yl]-2-(morpholin-4-yl)ethyl}quinoline-6-carboxamide::US10167281, Compound 115::US9718812, 115
SMILES FC1(F)CCC(CC1)c1ncc(s1)C(CNC(=O)c1cccc2ncccc12)N1CCOCC1
InChI Key InChIKey=VNKMAMKPIJLLQF-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 267190
Affinity DataIC50: 117nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:YO-PRO -1 is a fluorescent DNA-binding dye with a MW of 374 Da (Molecular Probes, cat. Y3603). This method is based upon the presumed ability of YO-P...More data for this Ligand-Target Pair
Affinity DataIC50: 117nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:YO-PRO -1 is a fluorescent DNA-binding dye with a MW of 374 Da (Molecular Probes, cat. Y3603). This method is based upon the presumed ability of YO-P...More data for this Ligand-Target Pair