BDBM267184 2-chloro-N-[2-(4,4-difluoropiperidin-1-yl)-2-[2-(hydroxymethyl)-1,3-thiazol-5-yl]ethyl]-5-(5-fluoropyrimidin-2-::US10167281, Compound 112::US9718812, 112
SMILES OCc1ncc(s1)C(CNC(=O)c1cc(ccc1Cl)-c1ncc(F)cn1)N1CCC(F)(F)CC1
InChI Key InChIKey=PIYFSKXRPDZBQR-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 267184
Affinity DataIC50: 119nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:YO-PRO -1 is a fluorescent DNA-binding dye with a MW of 374 Da (Molecular Probes, cat. Y3603). This method is based upon the presumed ability of YO-P...More data for this Ligand-Target Pair
Affinity DataIC50: 119nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:YO-PRO -1 is a fluorescent DNA-binding dye with a MW of 374 Da (Molecular Probes, cat. Y3603). This method is based upon the presumed ability of YO-P...More data for this Ligand-Target Pair