BDBM267176 N-[2-(4,4-difluoropiperidin-1-yl)-2-(1,3-oxazol-5-yl)ethyl]-2,6-dimethylbenzamide::US10167281, Compound 46::US9718812, 46
SMILES Cc1cccc(C)c1C(=O)NCC(N1CCC(F)(F)CC1)c1cnco1
InChI Key InChIKey=DKVVHGBDOCQCAB-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 267176
Affinity DataIC50: 18nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:YO-PRO -1 is a fluorescent DNA-binding dye with a MW of 374 Da (Molecular Probes, cat. Y3603). This method is based upon the presumed ability of YO-P...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:YO-PRO -1 is a fluorescent DNA-binding dye with a MW of 374 Da (Molecular Probes, cat. Y3603). This method is based upon the presumed ability of YO-P...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced calcium mobilization incubated for 30 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced calcium mobilization incubated for 30 mi...More data for this Ligand-Target Pair