BDBM26698 7-chloro-6-fluoro-9-(propan-2-yl)-1H,3H,4H,9H-quinolino[2,3-c][1,2]oxazole-3,4-dione::Isoxazoloquinolinedione, 6

SMILES CC(C)n1c2noc(=O)c2c(O)c2cc(F)c(Cl)cc12

InChI Key InChIKey=UDSJMCNBYOMONW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26698   

TargetSerine/threonine-protein kinase pim-1(Human)
Abbott Laboratories

LigandPNGBDBM26698(7-chloro-6-fluoro-9-(propan-2-yl)-1H,3H,4H,9H-quin...)
Affinity DataKi:  12.3nM ΔG°:  -10.7kcal/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Abbott Laboratories

LigandPNGBDBM26698(7-chloro-6-fluoro-9-(propan-2-yl)-1H,3H,4H,9H-quin...)
Affinity DataKi:  62.8nM ΔG°:  -9.72kcal/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2009
Entry Details Article
PubMed