BDBM26696 ethyl 3-methyl-4,8-dioxo-9-oxa-3-azatricyclo[8.4.0.0^{2,7}]tetradeca-1(10),6,11,13-tetraene-6-carboxylate::pyridone-based compound, 24

SMILES CCOC(=O)C1=C2C(N(C)C(=O)C1)c1ccccc1OC2=O

InChI Key InChIKey=YQUCNCKNGPDWCY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26696   

TargetSerine/threonine-protein kinase pim-1(Human)
Valeant Pharmaceuticals Research and Development

LigandPNGBDBM26696(ethyl 3-methyl-4,8-dioxo-9-oxa-3-azatricyclo[8.4.0...)
Affinity DataIC50: 2.00E+4nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2009
Entry Details Article
PubMed