BDBM26667 (2S)-5,7-dihydroxy-2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one::(S)-5,7-dihydroxyflavanone::CHEMBL399910

SMILES c1ccc(cc1)[C@@H]2CC(=O)c3c(cc(cc3O2)O)O

InChI Key InChIKey=URFCJEUYXNAHFI-UHFFFAOYSA-N

Data  6 IC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 26667   

TargetSerine/threonine-protein kinase pim-1(Human)
Loma Linda University

LigandPNGBDBM26667(CHEMBL399910 | (2S)-5,7-dihydroxy-2-phenyl-3,4-dih...)
Affinity DataIC50: 1.07E+5nMpH: 7.0 T: 2°CAssay Description:The 96-well flat-bottomed plates were coated with recombinant GST-BAD. After the plates were blocked, the reaction buffer containing test compound an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Loma Linda University

LigandPNGBDBM26667(CHEMBL399910 | (2S)-5,7-dihydroxy-2-phenyl-3,4-dih...)
Affinity DataIC50: 1.07E+5nMAssay Description:Inhibition of PIM1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM26667(CHEMBL399910 | (2S)-5,7-dihydroxy-2-phenyl-3,4-dih...)
Affinity DataIC50: 7.91E+3nMAssay Description:Inhibition of human CYP1A1 by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM26667(CHEMBL399910 | (2S)-5,7-dihydroxy-2-phenyl-3,4-dih...)
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of human CYP1B1 by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM26667(CHEMBL399910 | (2S)-5,7-dihydroxy-2-phenyl-3,4-dih...)
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of human CYP1A2 by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM26667(CHEMBL399910 | (2S)-5,7-dihydroxy-2-phenyl-3,4-dih...)
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM105 using HPPA as substrate after preincubated for 15 min followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed