BDBM26661 7,3,4,5-tetrahydroxyflavone::7-hydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one

SMILES Oc1ccc2c(c1)oc(cc2=O)-c1cc(O)c(O)c(O)c1

InChI Key InChIKey=CCCIGFPBADVTFE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 26661   

TargetSerine/threonine-protein kinase pim-1(Human)
Loma Linda University

LigandPNGBDBM26661(7-hydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-...)
Affinity DataIC50: 7.80E+3nMpH: 7.0 T: 2°CAssay Description:The 96-well flat-bottomed plates were coated with recombinant GST-BAD. After the plates were blocked, the reaction buffer containing test compound an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Loma Linda University

LigandPNGBDBM26661(7-hydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-...)
Affinity DataIC50: 7.76E+3nMAssay Description:Inhibition of PIM1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase S(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM26661(7-hydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed