BDBM26644 (5Z)-5-[(3-chlorophenyl)methylidene]-1,3-thiazolidine-2,4-dione::thiazolidine-2,4-dione, 22a

SMILES OC1=NC(=O)C(S1)=Cc1cccc(Cl)c1

InChI Key InChIKey=DTXPSQFSJWKKSG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26644   

TargetSerine/threonine-protein kinase pim-1(Human)
Medical University of South Carolina

LigandPNGBDBM26644((5Z)-5-[(3-chlorophenyl)methylidene]-1,3-thiazolid...)
Affinity DataIC50: 600nMpH: 7.0 T: 2°CAssay Description:The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Medical University of South Carolina

LigandPNGBDBM26644((5Z)-5-[(3-chlorophenyl)methylidene]-1,3-thiazolid...)
Affinity DataIC50: 40nMAssay Description:The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2009
Entry Details Article
PubMed